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Audio Recording May 24, 2021 at 12:02:51 PM

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Common Non-contraceptive Health Benefits of OCs

Reduced risk of: Dysmenorrhea Menorrhagia Endometriosis Premenstrual symptoms Hyperandrogenism (acne, hirsutism) Ovarian cysts Benign breast disease Cancer (ovarian, uterine, colorectal) Perimenopausal vasomotor symptoms Pelvic inflammatory disease

Audio Recording May 17, 2021 at 5:31:53 PM

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Renin-Angiotensin-Aldosterone  System (RAAS)

Na + / water retention K +  elimination Aldosterone Increased  Plasma Volume Increased   blood   pressure  in  susceptibles Water   retention-related   symptoms ( oedema ,  bloating ,  weight   gain ) Angiotensin I Renin substrate (angiotensinogen) Renin + Estrogen Angiotensin II Drospirenone

Audio Recording May 19, 2021 at 10:31:10 AM

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Benefits of  antimineralocorticoid  and antiandrogenic activities

Drospirenone Antimineralocorticoid Antiandrogenic Progesterone-like effects on  sodium and water retention: Bloatedness  / Breast Tension   Body weight   Other perimenstrual symptoms    Blockage of androgen receptor: Seborrhoea   Acne   Hirsutism 

Audio Recording May 24, 2021 at 12:25:05 PM

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Satisfaction with study treatment (Yasmin ®  extended)

Foidart et al. Contraception 2006;73(1):34–40

Audio Recording May 24, 2021 at 12:26:24 PM