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Vaccines 2. Dr. Hend Abdallah Al far H [email protected].
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Vaccine carriers. 2. Attempts are being made to deliver vaccines through carriers as they control the spatial and temporal presentation of antigens to immune system thus leading to their sustained release and targeting..
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To enhance the immune response of weak antigens. Maximum protection with less number of administration. Protect from acidic degradation in oral delivery. Induction of more prolonged immune responses with controlled release of antigen.
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Natural Protein: gelatin, albumin, Collagen . Polysaccharides: alginate, dextran, Chitin, chitosan . Lipids: Lecithin, liposomes. Disadvantages Poor batch-to-batch reproducibility Specific condition for the degradation and vaccine release Potential antigenicity Synthetic.
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Synthetic phospholipid spheres encapsulating Antigen. Act as Antigen delivery vehicle and adjuvant..
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Depending on the solubility of the antigen, it can be....