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[Audio] ENZYME STRUCTURE & FUNCTION Ribonuclease The molecular engine of RNA metabolism and regulation..
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[Audio] image.png THE RNA DEGRADER Molecular Scissor "Catalyzes the degradation of RNA into smaller components." Cleaves phosphodiester bonds. image.png Ensures cellular homeostasis. image.png.
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[Audio] Mechanisms of Cleavage image.png image.png Endoribonucleases Exoribonucleases Cleaves internal RNA sites. Degrades from terminal ends..
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[Audio] Primary RNase Families image.png image.png image.png image.png RNase A RNase H RNase III RNase P Cleaves RNA-DNA hybrids. Processes double-stranded RNA. Digests single-stranded RNA. Catalytic tRNA ribozyme..
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[Audio] image.png image.png Catalytic Mechanism RNase A Two-Step Pathway 1. Transphosphorylation His-12 extracts proton. 2. Hydrolysis His-119 activates water..
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[Audio] Biological Imperatives image.png image.png image.png Innate Immunity Gene Regulation RNA Maturation Processing functional transcripts. Controlling transcript stability. Defending against pathogens..
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[Audio] image.png Biotechnology Applications RNA sequencing preparation. image.png Gene expression quantification. image.png DNA isolate purification. image.png.
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[Audio] THERAPEUTIC HORIZONS From Enzyme to Drug Exploiting RNase cytotoxicity for targeted anti-cancer therapeutics..
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[Audio] Image Sources image.png https://cdn.rcsb.org/images/structures/1rbx_chain-A.jpeg Source: www.rcsb.org image.png Source: www.sciltp.com https://pipette.com/hs-fs/hubfs/How%20to%20Choose%20the%20Right%20Pipette%20for%20Your%20Lab%20Application.jpg?width=920&height=700&name=How%20to%20Choose%20the%20Right%20Pipette%20for%20Your%20Lab%20Application.jpg image.png Source: pipette.com.