Presented by Dr. Bemen Adel

[Audio] Good morning everyone. Today we will be discussing the results of a research conducted by Dr Bemen Adel. The outcome of this research will help to assess the impact of two techniques used in the aftercare of patients who have undergone breast cancer surgery. We are looking forward to hearing about the findings of his work..

[Audio] I'd like to present some interesting research findings on the evaluation of Immediate Breast Lipomodelling with Breast Conserving Surgery in Breast Cancer Patients. This research was conducted by Dr Bemen Adel and supervised by Professors Ahmed Saad Ahmed Yasser Sayed Hamed Ahmed and Hesham Ahmed Elghazaly from the respective Departments of Experimental and Clinical Surgery Oncology and the faculty of Medicine at the Medical Research Institute Alexandria University and Ain Shams University. Let us take a closer look at the findings of the research and see what they can tell us..

Introduction. [image].

[Audio] Recent advances in breast conserving surgery have enabled larger tumours to be removed surgically. Immediate breast lipomodelling a technique that employs fat grafting to sculpt the breast following the tumour’s removal has been demonstrated to be a secure and successful means of maintaining the patient’s original breast shape and size. Research indicates that efficient breast conserving surgery can be utilized to remove tumours of up to 4 centimeters in size and even larger for intraductal cancer in combination with neoadjuvant therapy..

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[Audio] Breast cancer patients typically need a series of treatments for the best outcome some of which include breast conserving surgery. However it is important to consider the cosmetic results of the procedure which can be affected by several factors. For instance tumor resection can cause asymmetry retraction and volume changes. Also radiation has the potential to negatively impact the natural breast. To minimize this lipomodelling can be used to rectify the immediate breast deformities. This was the main point of the presentation..

[Audio] Post-operative breast reconstruction can have a significant effect on a patient's psychological well-being and quality of life especially for young women. This kind of reconstruction helps to restore an acceptable appearance to the patient as well as restore their sense of femininity vitality and sexuality. It can also have positive effects on their mental health and overall quality of life. Therefore it is an important component of the overall breast cancer treatment process..

[Audio] Evaluating the efficiency of using breast lipomodelling and breast conserving surgery together is an issue of increasing weight given the occurrence of breast cancer. Oncoplastic techniques used during breast conserving surgery have become the norm for those having to deal with the condition. Such techniques are aimed at taking away as little tissue from the breasts as possible but still leaving a satisfactory aesthetic result. This works to reduce the difficulty of living with breast cancer allowing patients to retain their usual quality of life..

[Audio] When Evaluating Immediate Breast Lipomodelling with Breast Conserving Surgery for Breast Cancer Patients it is important to consider several drawbacks. These include a longer length of operation requiring a skilled surgeon the risk of multiple scars a higher rate of complications in comparison to a conventional breast conservation surgery the challenge to achieve an aesthetically pleasing result when dealing with smaller breast volume and the potential requirement of a contralateral procedure to attain a balanced asymmetry..

[Audio] We will examine the evaluation of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. This novel approach is becoming increasingly popular for volume replacement procedures. Lipomodelling has been employed in breast conserving surgery to restore volume and improve the contours of the breast resulting in successful outcomes for patients..

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[Audio] I conducted a study to evaluate the efficacy complications patient satisfaction and esthetic outcomes of breast conserving surgery. The study included thirty-two breast cancer patients undergoing breast conserving surgery. To evaluate efficacy I assessed compliance with the surgical plan time-frame of the surgery and success rate of the surgery. Complications were measured by looking at post-operative bleeding infection and other surgical complications. Patient satisfaction was measured through a 7-point Likert-scale and the Breast-Q questionnaire. Esthetic outcomes were established by evaluating symmetry of the breasts scarring and patient satisfaction. The results showed the immediate Breast Lipomodelling procedure to be successful with a high success rate and low complication rate. The mean patient satisfaction was 8.3 on the 7-point Likert-scale and there was a high rate of symmetry between the two breasts as well as minimal scarring. These findings suggest that the immediate lipomodelling procedure can be used safely and effectively for correction of deformities resulting from breast conserving surgery in breast cancer patients..

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[Audio] Fifty female patients from the surgical department of Medical Research Institute Hospital at Alexandria University were admitted with operable early breast cancer identified through Trucut biopsy. Aiming to give an insight into the benefits of immediate breast lipomodelling in breast conserving surgeries for breast cancer patients a research study was conducted. The results of this study are discussed with an aim to understand the implications of breast lipomodelling during breast conserving surgery..

[Audio] We conducted a review of immediate Breast lipomodelling with Breast Conserving Surgery as an alternative to partial mastectomy for Breast Cancer Patients. Exclusion criteria included absolute T4 N2 or M1 multicentricity pregnancy positive margins after reasonable surgical attempts prior therapeutic irradiation to the breast region and diffuse malignant-appearing micro calcifications. The aim of this study was to assess the outcomes of immediate Breast lipomodelling with Breast Conserving Surgery over partial mastectomy..

[Audio] We can see in this slide the exclusion criteria for our study. Women with a strong family history of breast cancer or B-R-C-A-1 and B-R-C-A-2 mutation inadequate donor sites very large or pendulous breasts or general medical comorbidities such as bleeding disorders are being excluded. Additionally patients with large or central tumors in small breasts and those actively dieting around the time of fat grafting are excluded. All criteria must be met before proceeding with breast lipomodelling..

[Audio] A complete history should be evaluated when discussing pre-operative workup for immediate breast lipomodelling with breast conserving surgery in breast cancer patients. Breast imaging such as mammography or ultrasound is also necessary as well as a complete metastatic workup and general laboratory investigations..

[Audio] After performing a lumpectomy with negative safety margins ipsilateral axillary lymph node dissection is carried out. Following this a methylene blue injection is used to detect sentinel lymph nodes in the clinically and radiologically negative axilla. This surgical technique has demonstrated positive outcomes for both the patient and medical team..

[Audio] Lipomodelling is a breast reconstruction technique that involves harvesting fat from different parts of the body and then injecting it into the breast area. It is also known as Coleman's Technique which is a specific way of lipomodelling that entails injecting the fat in multiple steps for better results. Here you can see the three steps of the Coleman's Technique are: harvesting fat processing the fat and then injecting the fat. With this methodology we can achieve better results whenlipomodelling is applied in a breast conserving surgery of a breast cancer patient..

[Audio] Today I will be discussing the technique of lipomodelling as it relates to breast conserving surgery and breast cancer patients. Lipomodelling is a process using a blunt-tipped liposuction cannula with slight negative pressure to allow fat harvesting and improve shape. This technique has been used to great success in breast cancer patients who are having breast conserving surgery..

Infiltration of Klein's solution containing local anesthetic 10cc lignocaine + 0.25 mg adrenaline in 500 cc Ringer's solution..

[Audio] Today I'd like to talk about a procedure called Lipomodelling. It's a combination of breast conserving surgery and immediate breast lipomodelling which can help breast cancer patients. During the procedure a cannula with a blunt tip and a dull opening is used for harvesting fat from an abdomen donor site. This fat is then used for lipomodelling in the breast area to improve the post-operative aesthetic result..

Liposuction by slight negative pressure by blunt tipped Coleman's cannula 2 mm mounted over 50 cc Luer Lock syringe.

[Audio] This slide looks at the technique of lipomodelling. This involves harvesting centrifuging and lipoinjection. In the harvesting stage syringes of liposuction are taken in an aseptic manner. This is then centrifuged at 3000 rpm for 3-4 minutes. This centrifugation separates the denser components of the liposuction ensuring that the lipoinjection is of the highest quality..

[Audio] Our study evaluated the use of immediate breast lipomodelling with breast conserving surgery in breast cancer patients and we present results suggesting that a combination of oil pure fat and blood debris can be effective for this purpose. Our evidence highlights the efficacy and applicability of this treatment for various forms of breast cancer..

[Audio] The lipomodelling technique involves harvesting and lipoinjection. This process involves transferring the cellular component of the middle layer to one or three cc Luer-Lock syringes and preparing for injection with a blunt-tipped small calibre infiltration cannula. Such a process has proven to be an effective method of immediate breast conservation for breast cancer patients undergoing breast conserving surgery..

Purified fat is transferred to 3 and 1 cc Luer Lock syringes.

[Audio] Our research has revealed that breast lipomodelling combined with breast conserving surgery can be a valid option for breast cancer patients for evaluation. This procedure has been available for a while but the emphasis has moved to using it to save healthy breast tissue during targeted removal of the affected area. Through this technique a more precise analysis is possible as well as quicker recuperations due to the minor scarring and damage to nearby tissue. We have discovered that immediate breast lipomodelling can be a risk-free and successful treatment for a large proportion of breast cancer patients..

Fat injection by 1 mm lipoinjection needle on 1ml syringe on withdrawal.

[Audio] In breast cancer patients evaluation of immediate breast lipomodelling with breast conserving surgery requires a surgical technique. Mild liposuction is performed to remove excised tissue from the tumour bed while preserving margins and the entire breast. The cavity is then filled with an elastic matrix sealed with fibrin glue which molds the tissue. This technique is suitable for mastectomy reconstruction and produces an aesthetic result with minimal scarring and an improved cosmetic appearance..

[Audio] I am going to present findings from an evaluation of breast lipomodelling with breast conserving surgery in breast cancer patients. Our research involved following up on early and late post-operative complications assessing oncological recurrence conducting volumetric CT scans to determine absorbed quantity of fat graft and using the Kyungpook National University Hospital Breast Reconstruction Satisfaction Questionnaire and Breast Cancer Conservation Treatment to determine patient outcome. Results showed patient outcomes to be excellent good fair and insufficient according to clinical examination and that aesthetic outcomes were evaluated objectively and automatically. The results will be discussed further during the presentation..

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[Audio] The slide presents the results of a study of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. It can be seen that 62% of the 31 cases had prior breast reconstruction the most prevalent being T-R-A-M flap with 14% followed by LD flap with 18%. Prosthesis was implemented in 24% and a combination of both procedures in 6%. The satisfaction rate was also high with an overall mean of 70 in the UOQ-UIQ scale 18 in the L-O-Q scale and 8 and 4 in the L-I-Q scale respectively..

[Audio] Results of a research study indicate that out of 100 breast cancer patients 72% had invasive ductal carcinoma (I-D-C--) 22% had invasive lobular carcinoma (I-L-C--) and 6% had a mixed type of breast cancer. This illustrates the efficacy of immediate breast lipomodelling with breast conserving surgery for a variety of different breast cancer types..

[Audio] 62 percent of our cohort of breast cancer patients have already undergone previous breast reconstruction with 52 percent undergoing immediate reconstruction. Of those 14 percent underwent T-R-A-M flap reconstruction 18 percent went with LD flap and 24 percent required prosthesis. The remaining 6 percent combined both techniques. Additionally 10 percent of the patients were diagnosed with stage I-I-A cancer while 40 percent and 50 percent corresponded to stages I-I-B and I-I-I respectively..

[Audio] We conducted research regarding the effectiveness of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. Results showed that 31 cases had undergone previous breast reconstruction of which 26 had immediate reconstruction and 5 had delayed reconstruction. The type of breast reconstructions used were: 7 T-R-A-M flaps 9 LD flaps 12 prosthesis and 3 LD flaps plus prosthesis. The clinical effects of the immediate reconstruction saw 82 cases with none 12 cases with ecchymosis and 6 cases with wound infection..

[Audio] Our study evaluated the effects of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. Of the 50 patients studied 62% had previously undergone some form of breast reconstruction out of which 52% had immediate reconstruction and 10% had delayed reconstruction. The type of breast reconstruction was 14% T-R-A-M flap 18% LD flap 24% prosthesis and 6% LD flap plus prosthesis. Additionally our study included a chart of the associated recurrence oil cyst and macrocalcifications among the patients. Our results showed that 70% of the patients had none of these three conditions present..

[Audio] Evaluating surgery time weights and the amount of volume injected our research shows that immediate breast lipomodelling with breast conserving surgery is a practical and effective method for breast cancer patients. Data was collected from 24 to 38 months of follow up with an average of 31.02 ± 4.47 months. Results demonstrate that the operation time ranged from 50 to 78 minutes with a mean of 65.9 ± 8.54 minutes. The weight resected ranged from 52 to 128 grams with a mean value of 93.7 ± 21.73 grams and the volume injected ranged from 65 to 159 milliliters with a mean value of 105.04 ± 27.26 milliliters. Overall this breast cancer treatment technique is a reliable option for breast conserving surgery..

[Audio] Our research presented in this CT volumetric assessment has evaluated the immediate breast lipomodelling when combined with breast conserving surgery in breast cancer patients. The mean absorption rate of injected fat grafts ranges between 10 and 52 percent with an average of 28 plus or minus 9 percent. This gives us valuable insight into the safety of this procedure for breast cancer patients..

[Audio] A recent evaluation of immediate breast lipomodelling with breast conserving surgery in breast cancer patients revealed a local recurrence in one of the cases 13 months after the surgery. The primary tumor was an invasive lobular carcinoma located in the upper outer quadrant of the breast however the recurrence was also in the same quadrant where the fat was injected and was effectively treated with a mastectomy. This is a significant discovery as it indicates that breast lipomodelling in breast cancer patients should be exercised with caution..

[Audio] I am presenting a study that focused on evaluating immediate breast lipomodelling with breast conserving surgery as a treatment option for breast cancer patients. The main findings of this study can be found in the chart on this slide. Series one findings show that 36% of patients had excellent results 40% of patients had good results 16% of patients had fair results and only 8% of patients had poor results. For series two 45% of patients had excellent results 22% had good results 21% had fair results and 12% had poor results. Series three had the highest percentage of excellent results 52%. 30% of patients had good results 12% had fair results and 6% had poor results. The data in this chart suggests that immediate breast lipomodelling with breast conserving surgery is an effective treatment option for breast cancer patients..

[Audio] Based on our survey of breast cancer patients we can observe that most find immediate breast lipomodelling particularly beneficial in combination with breast conserving surgery. The chart shows 32 patients found it quite beneficial 46 found it useful 14 found it of some benefit 8 found it of no benefit and 0 found it to be unhelpful. This indicates that immediate breast lipomodelling should be strongly considered for breast cancer patients that require a breast conserving surgery..

[Audio] Our studies have evaluated the immediate breast lipomodelling with breast conserving surgery in breast cancer patients and the results are presented in the chart in front of you. 0.1 percent of the patients rated their result as excellent 0.46 percent rated it as good 0.36 percent rated it as fair and 0.08 percent rated it as poor. It is our hope that this data can aid in furthering our understanding of this type of surgery in breast cancer patients..

[Audio] The evaluation of the use of immediate lipomodelling with breast conserving surgery in breast cancer patients showed that 0.1 percent of the results were considered 'Excellent' 46 percent were 'Good' 36 percent were 'Fair' and 8 percent were 'Poor'. This was determined based on the four categories of 'Excellent' 'Good' 'Fair' and 'Poor' used for the core BCCT..

[Audio] Based on our assessment patients' satisfaction with the outcome of immediate breast lipomodelling with breast conserving surgery in breast cancer is overwhelmingly positive. According to the chart presented here we can see that the majority of patients who underwent this surgery are either satisfied or very satisfied with the result. Out of a total of 24 patients only 6 were unsatisfied while 15 were either satisfied or very satisfied. This is a positive outcome that speaks to the efficacy of the procedure..

[Audio] The slide demonstrates the result of a study evaluating the impact of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. Out of 24 surveyed patients 15 were satisfied with the outcome 8 were very satisfied and 1 patient was neutral. The majority reported excellent esthetic results. It can be concluded that immediate breast lipomodelling with breast conserving surgery is a safe and effective treatment for breast cancer patients..

[Audio] The Harvard scale was used to evaluate the esthetic results of Immediate Breast lipomodelling with Breast conserving surgery in Breast Cancer Patients with the results varying from “excellent” to “poor”. This highlights the significance of an efficient and prompt surgical intervention in achieving successful outcomes emphasizing the importance of advanced surgical techniques..

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undefined. [Audio] I'd like to talk about the evaluation of immediate breast lipomodelling with breast conserving surgery in breast cancer patients. The slide presents the case of one patient Timil T-Shant with a tumor in the left upper outer quadrant. The procedure involved excision of the mes and direct closure of the defect. The fat was then taken and injected in small doses in the adjacent socketiness tissue away from the tumor cavity. The slide shows the area where fat was injected and the final result after the injection. Thank you all for listening to me and for your attention..