[Audio] My greating to one and all me omkar anandkar from first year pharm D Today we are going to study about radiopharmaceuticals .. 

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[Audio] The radioactivity The phenomenon of spontaneous emission of certain kind of invisible radiation by some substance is called radioactivity.
The radioactive substance used in diagnosis and treatment of some disease like cancer are called radiopharmaceuticals.
As we see in the image the radionuclide is linked to target molecule and treats cancer cell .. 

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[image] Radionuclide
(Diagnostic or
Linker Molecule
Cancer Cell
Binding

The phenomenon of spontaneous emission of certain kind of invisible radiation by some substance is called radioactivity.

The substance which slow such radiation are called as radioactive substance.

Radiopharmaceuticals – radioactive substance used in diagnosis and treatment of some disease like cancer are called radiopharmaceuticals.

[Audio] What are Radioactive substance Substance having property of emitting rays or particles which affects the photographic plate .
The elements are known as radioactive because they are unstable and undergo decomposition along with emission of radiation or rays. 

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Radioactive substances have a property of emitting rays or particles which affect the photographic plate. Forty radioactive element are known which are arranged as Uranium series ,thorium series and actinium series.

The element are known as radioactive because they are unstable and undergo decomposition along with emission of radiations or rays

Radiopharmaceutical are drugs that contain radioactive isotopes and are used for diagnostic or therapeutic purpose. The radioactive isotopes used in radio pharmaceutical emit radiation that can be detected by imaging device such as gamma camera , PET scanners , SPECT scanner . This allows physicians to visualize the metabolic activity of various organs or tissues and to diagnose diseases such as cancer , heart disease or neurological disorders

[Audio] The radiation or rays which are emitted are follow Alpha rays
Beta rays Gamma rays. 

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The radiations or rays which are emitted are follow

[Audio] The Alpha rays They carry 2 positive charge They have a mass of 4 amu They have low penetrating power. 

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These rays or particles have low penetrating power

They have positive charge and can be detected by a strong magnetic filed

Heavy metals have capacity to emit such type of rays

All alpha particles are having the same energy

The penetrating power of alpha rays is less as compared to other emission

Because of low penetrating power of alpha particles, elements which emit alpha rays do not find use in biological application because they cannot penetrate tissue

[Audio] The emission of alpha particle The number decreases by 2 unit and mass number decreases by 4 unit.. 

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During emission of an alpha particle atom number decreases by 2 units and mass number decrease by 4 units

What happens when alpha -particle is emitted?

[Audio] Beta rays They have negligible mass Beta particle carry one unit of negative charge. 

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1 electrically positive charged particle which are called positrons

2 electrically negatively charged particles which are called Negatrons

These particles are usually accompanied by gamma radiation. Beta particles have less ionizing power then alpha particle

Beta particle carry one unit of negative charge

[Audio] These have 2 type 1 electrically positive charged particle which are called positrons 2 electrically negatively charged particles which are called Negatrons. 

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[image] Beta Decay
Beta decay is radioactive day that either releases an
electron (beta minus) or positron (beta plus).
14
borcn•tO
antineutrino electron
neutrino
positron

During the emission of beta particle atomic number increases by 1 unit and there is no change in the mass number

[Audio] Gamma rays These have been more penetrating then alpha and beta rays They have no mass or charge They are uncharged and have poor ionizing power
These rays are neutral that is do not carry charges. 

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These have been more penetrating then alpha and beta rays

They are having the same character as that of very short electromagnetic waves called x-rays

Gamma rays are produced during distintegration of radioactive substance along with beta radiation and during nuclear fission

They are uncharged and have poor ionizing power

These rays are neutral that is do not carry charges

The particle of these rays has negligible mass

[Audio] Gamma rays are produced during distintegration of radioactive substance along with beta radiation and during nuclear fission. 

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The quantity of the radioelement which disappears in units c rate of disintegration is directily proportional to the amount present

[Audio] The unstable atom have some chemical and properties as parent element but different kinetic properties
They are of 3 type isotopes, isobars , isotones 1The atoms of the same element which have the same atomic no. but different mass number are knows as isotopes 2Atoms of different element having the same mass no. but different atomic no. are called isobars 3Atoms of different elements containing the same no. of neutrons but different no. of total nucleons are called isotones. 

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The unstable atom have some chemical and properties as parent element but different kinetic properties

The atoms of the same element which have the same atomic no. but different mass number are knows as isotopes

Atoms of different element having the same mass no. but different atomic no. are called isobars

Atoms of different elements containing the same no. of neutrons but different no. of total nucleons are called isotones

[Audio] Radioisotopes
There are 2 types of radioisotopes First Natural radionuclide Second Artifical radionuclides. 

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1.Natural radionuclide – high atomic weight[above 40]

2.Artifical radionuclides- original inert

Active when controlled radiation bombarded                on it

[Audio] Radioactive Decay Constant. Radioactive Decay Constant. 

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Decay Constant of Radioactive elements Calculator | Calistry

Lamda-is the decay constant No is the number of atoms of radioactive element orignally present N is the number of atoms of the same radioactive element present at time t

[Audio] Half life Time required for a radioactive isotope to decay to one half of its initial value .. 

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C.3 Calculating the decay constant (SL) - YouTube

Time required for a radioactive isotope to decay to one half of its initial value .

It is denoted by T1/2 , lamda –disintegration constant.

Radiopharmaceuticals 

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My greating to one and all me omkar anandkar from first year pharm D

Today we are going to study about radiopharmaceuticals .

avatar

The radioactive substance used in diagnosis and treatment of some disease like cancer are called radiopharmaceuticals.

As we see in the image the radionuclide is linked to target molecule and treats cancer cell .

Substance having property of emitting rays or particles which affects the photographic plate .

The elements are known as radioactive because they are unstable and undergo decomposition along with emission of radiation or rays

The radiation or rays which are emitted are follow

The number decreases by 2 unit and mass number decreases by 4 unit.

They are of 3 type isotopes, isobars , isotones

1The atoms of the same element which have the same atomic no

but different mass number are knows as isotopes

2Atoms of different element having the same mass no

3Atoms of different elements containing the same no

First Natural radionuclide 
Second Artifical