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INTRAVENOUS ROUTE OF ADMINISTRATION GROUP 4 - SECTION C

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When rapid absorption is needed When fluid cannot be taken by mouth When the medication to be administered is too irritating to be injected into the skin or muscles.

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The procedure is explained to the patient (name of the drug, expiration date, etc)

Make sure t hat the IV line is intact and not leaking

A lert the health care professional  for any feelings of discomfort

Health care professional determines the amount of time over which the drug should be delivered (calculated in cc/minute)

Healthcare professional administers the IV drug via standard IV catheter in the peripheral vein or via central venous catheter (CVC)

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b. Cepahilic vein in anatomical snuff box

Cephalic
vein
teachmeanatomy
Hurran Ana•.om/ Web.

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3. Cubital fossa Median antecubital, cephalic and basilic veins

Bice
Brachii
Biceps brachii
tendon
Brachoradialis
TAT
edian nerve
rachial artery
ronator teres
lexor carpi
radialis

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Advantages of Intravenous Route of Drug administration

Bioavailability is 100% Immediate   effect  (suitable for emergencies) Can be given to unconscious patients Avoids first-pass  metabolism Achieves  predictable and precise control over drug plasma levels  compared to other routes Drugs can be  delivered at a uniform rate  with reproducible effects Very large volume of infusion can be administered Provides  distribution of the exact amount  of the drug Provides  convenience to the patient Does not harm the digestive system  since it bypasses them No issue related to unpleasant odor and taste

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IV injection may  induce hemolysis and other similar conditions if the drug is administered too rapidly.

This route has high probability of bacterial contamination, so strict aseptic conditions are needed

Depot preparations cannot be given by IV route

Once drug is injected, its action cannot be halted and cannot be remove

Extravasation of some drugs can cause injury, necrosis, and sloughing of tissues

Severe adverse effect especially when organs such as liver, heart, brain are involved in toxicity.

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Drugs typically given intravenously cancer chemotherapeutics:  doxorubicin, vincristine, cisplatin, paclitaxel antibiotics : vancomycin, meropenem, gentamicin antifungals:  micafungin, amphotericin pain relief medications:  hydromorphone, morphine

MORPHINE C
USP
nc 55151>204-20
Vancomycin
for
Injection, USP
per vial
For Intravenous
b. Further
Diluted use
JgaL,•
67.57
DOXOrubicin
Hydrochloride
usp
ONLY
SOLUTION jj Mylat
r.atcn: Cytotoxic Agent
Single-Dose
AMPHOTERICII
For injection
iach vial contains
50 mg
•t&Reg.N0. IA IW47

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Adenosine
Injection, USP
mg per 30 m
(3 rnq rnLj
For
Adenosine
Injection, USP
60 mg per 20 mL
CEO

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8801m
Nutrilipid
0264-4460-30
250 mL
SET
20% I.V.
B, BRAUN
Fat Emulsion
A
ADD

Intravenous Fat Emulsion (IVFE) Drugs ordinarily must be in aqueous solution; they must mix with the circulating blood and not precipitate from solution.  Fat emulsions have gained acceptance as an important source of calories and essential fatty acids for patients receiving parenteral nutrition.

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Local Complications Systemic Complications Infiltration Extravasation Thrombosis Thrombophlebitis Phlebitis Embolism -Pulmonary embolism -Air embolism             -Catheter embolism Hematoma Systemic Infection Speed shock Circulatory overload Allergic reaction

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Infiltration Presentation
Grade O
Grade
Grade O
Grade O

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to trauma of vetn
Vein
81CK)d clot
Cattk•ter in vetn
redness
inflammation

INTRAVENOUS ROUTE OF ADMINISTRATION GROUP 4 - SECTION C

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