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[Audio] D-N-A sequencing. DNA sequencing.
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[Audio] D-N-A sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine.
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[Audio] D-N-A sequencing, technique used to determine the nucleotide sequence of DNA (deoxyribonucleic acid). The nucleotide sequence is the most fundamental level of knowledge of a gene or genome. It is the blueprint that contains the instructions for building an organism, and no understanding of genetic function or evolution could be complete without obtaining this information..
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[image] base pairs n ucleotide sugar-phosphate backbone p base pairs hydrogen bonds @ Phosphate sugar nitrogen— contai ning bases.
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[Audio] First-Generation Sequencing Technology The first-generation sequencing technologies, which emerged in the 1970 seconds, included the Maxam-Gilbert method, discovered by and named for American molecular biologists Allan M Maxam and Walter Gilbert, and the Sanger method (or dideoxy method), discovered by English biochemist Frederick Sanger..