Atropine and its analogues

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Scene 1 (0s)

Atropine and its analogues.

Scene 2 (1m 11s)

. Afropine pyoauc-å exfyac]eÅ from—BUladonna AKLloid amme *Can cross BBB C.LJS efGc*s P." .s+effæts Heckanism of achon + Alyopine is a CompUifive antaaonis+ OF muco-rinic vecepfoys (Afropne binds fotHlreceefors in -»cømpe}åive manner yece+fors I-nve a affæb Aho Hougvex, is prsene i} On ovey@me the of.

Scene 3 (6m 11s)

. Hedlanism au;on a. subjspgs of muscaijnic Non-Select;ve a4;on achon of cårop•ne on receebE is 31. Cßlock;tb adonJ 8 nbibfrs achcM Blocarp;.

Scene 4 (8m 37s)

. pharmacolzcd au;ons Y."oSis J Hddr;asis Diffe»ence coeen cixcßx m muc(e F phncf0Y.

Scene 5 (12m 2s)

. Pupil Iris Lens allowed to bulge Muscle like a sphincter on a bottom SUSpensory ligaments are sla:k Ciliary muscle Lens pulled thin Suspensory ligaments are pulled tight.

Scene 6 (17m 2s)

open angle Lens closed angle Lens. Drainage of aqueous humor in open-angle glaucoma.

Scene 7 (18m 21s)

maco\osA x.t;ons:. O. yeceetors Due do Inhibition of rry5gle Abenæ of miofic Qdion Ermenanf Is h3AYiasiS which \asf foy 7 _ Accomddwn fir fox VSioK wwæprse c I ijt Due b of yæeetoys in Cilia-y muscle of ciliNd muscle pullina CoÅyad;on df -he SugpenS0$ Lismenfs Hoe flåfenecl lens focd (enall of lens.

Scene 8 (23m 21s)

. Pbaxrnaco(zLcal aå;ons Afyopne a] SO Causes , _ 'tt't p yessc.u-e Duefo inhibåion of L jecep In PDQ@lIa.3 mqSde muscle PORS of Canal of sc%lemm of aqueous bumoY tm IOP 6 Lacy;md secu;ons Due of ors in, eel 'ld.

Scene 9 (25m 23s)

. Pbaxrnaco(zLcal aå;ons Afyopne a] SO Causes , _ 'tt't p yessc.u-e Duefo inhibåion of L jecep In PDQ@lIa.3 mqSde muscle PORS of Canal of sc%lemm of aqueous bumoY tm IOP 6 Lacy;md secu;ons Due of ors in, eel 'ld.

Scene 10 (27m 27s)

. Plaa.ymacde-l a40hS:. Cardiovasc,dær ssfem Afro ne prouce.$ divægit effects an C.VS QCCOYd; to ose Effed of a+rop•me on heaå t. doses of Kiah C tess }han o.b [2-5 m;] Ini+ia..( lächdca.rdla Due b in i if;on of OIS on pyezapf;c neurons Ach release -This inoeqse in ue fo inhi of YH and 2 recef-iors• Afrop;ne blocks 00 _2 to ACR from exa-t in hem-I Ide.

Scene 11 (32m 27s)

. Phaxmacoløoicd cv.s;. Afr •ne iraqces g r3 mecharusm Effed of inneyvåe TnKbfi,o yecp}oys in bjcxA vessels of f rauc and agao.rn;nd Viscera.

Scene 12 (36m 16s)

. c.v.s . Atropine a type of se vonl Causes G)fr affecÅ;nJ net atroÉne is 6J/fh rorrrn( hen-rd nan-tic' gecause induces rrok, atropine a m OAU] 9 pe Of hag l;Hle or ro effed on blmd vessels effed BJcuQ.

Scene 13 (39m 30s)

. Phaxmacøl*ica.l O. Gasfro-irdesf;na.l fya4 • recep}ors in GIT Of ærsåÅsis - Hot-oevey, atropine ve±) effechve anfBærrxJic acouse, enfe.yic nervous em i S (bnbol/aÅ Via Other I hormones ije.uxo Afropine doesMf affec_} production of ffCl used for b€otrnénf of.

Scene 14 (41m 57s)

. Pharm acol?icd AU;ons O. Respiro*oy Afropine inhb•, Eyecee}ovs in Bro Secans Atropine for fkUmen} of aabin,k h? yeceßojg on [JJ yecqf Ydeqse Reve-15%6 of induced of receptors.

Scene 15 (44m 54s)

Pbaxmaco(äicd ac*ions . Afropine b, in b)Qolclex,. of Relax of Bladder *inåers Sloa;jns vo'ld;nå Afropine inhibits tecep+oys in nexves fe.MV Secpe*i0hS.

Scene 16 (47m 14s)

ac.t;ohS 9. nexvoqs S em Yll yecee in of cehfers Hd\ucänoåions C) Delirium 10 rn Deeess•ton Ipna-l.as+;na seda*iøn Vomtf;ns Cenier.

Scene 17 (49m 19s)

. 7hexapU;c disease. Complemenf%J apprnc}l he.oårnenf of paykGrvson6 Dopamine ye3foye normal ±iajeen excåcutctd CAchJ oru inhjbiåOYd t Gffds paFßnøn3 parrine @. Due cf vornå;ns ev io Brain "c di#YdZS Fundus exami ion *necka in uveifis and iritis.

Scene 18 (53m 12s)

9. Respira*o disorders Chvø%ie disease AsåKma Because,fhe bpexachve neuxd reflex viq nave ocoxolid Because, Nose p:åienfs experience reflex SAN AVN Ad pexaåive Ca.rof;4 Sinus reflexes Because, }hcse pa-+,enfs rnQd experience fo_infness clue +0 in vespnse +0 o-n the neck..

Scene 19 (56m 5s)

GIT Gav erg ux;n disorders opioid $enf J Abuse morphine asociated fi•equeh4 u.yina.b) f;equenc; engyegis •tn chiLdæn UXOli+KiQS'tS ConfracÅi0Yl of uxe±exa.l gmcofh muscle Fau pasqye o.

Scene 20 (58m 36s)

-frtuapeå;c O. Pye-amsthet;c of resprai0Yd Cen}ev @ Bronchoa,biion ions > of vorni%r$ cen}ex CkÖlin Neyve poison•tns Zases Cholinesterase inh;båors toxic* O. Exce$ive swee*tindqced bd ecy;ne 60.) eek *nAS.

Scene 21 (1h 3m 5s)

Afropine anu ues O. oph+ho.lrnå08d Scopolamine | 140moiY0f)i ne -3 )40dexOe (Jc)openfolote • vex Tiotropium Ions burnecliolifiium Hodexo-te >Tpvaåyopiurn [Atrovent' ac+;n.

Scene 22 (1h 5m 40s)

Atyop;ne u.r;ha.r disorders;. > turipané NpT0'9ium CTrogpiKaP3 > Sol ifenac-in C Hicfonoym@J O. P».eeyahons POå4Gnsoæ ollSease Aenzfrop;ne Cc.oserd;n J > Benzhexol TiemoY$ induced Which •mAuceA bd.

Scene 23 (1h 8m 45s)

Adverse efec*s:. mouth 2. Sanå edeg 3. low doses 0.2-2 uy;na.$ yeåehfioh 5. Censf;paåi0h 6. Res+lesshess Cchfusion Mod e.yåe closes HdluUhd;ohS 10. Deepesslon II. Collapse of and löxic Aoses > 10.

Scene 24 (1h 10m 9s)

ions T,o.p 2. Pros}åjc Because, Afrop;ne induce reiggf;0Fl 3. gecause, [Ajyop;ne Slows.

Scene 25 (1h 11m 16s)

Special afrepine on mice Afvopine inAuceg lhe When inejecåed info mice:- > Qes} lessness b-)o min > Runn'lno on {iptoes evechøn p" ne So Y)ame . A.XJ.S au;nå Arua.