[Virtual Presenter] The human body produces bilirubin through a process called heme catabolism. Bilirubin is a yellowish-red pigment that is found in red blood cells. When red blood cells are broken down, bilirubin is released into the bloodstream. The liver is responsible for the metabolism of bilirubin, and it works with other organs, such as the kidneys and spleen, to eliminate excess bilirubin from the body. The spleen is particularly important in this process, as it filters out foreign particles and substances from the blood, which helps to maintain the body's overall health. There are two main types of bilirubin in the body: biliverdin and bilirubin. Biliverdin is an intermediate compound that is produced during the early stages of heme catabolism, and it is converted into bilirubin. Bilirubin plays a crucial role in the body's iron metabolism, as it helps to transport iron from the liver to the bloodstream. Additionally, bilirubin is also involved in the production of bile, which helps to break down fats in the digestive system. In summary, bilirubin is a vital component of the human body, and it plays a key role in the process of heme catabolism, as well as in the body's overall health and functions.. 

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How Bilirubin Is Formed??. Man in a polo shirt. 

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[Audio] Bilirubin is a yellow pigment that is produced in the liver when red blood cells (erythrocytes) are broken down. Senescent erythrocytes, which are red blood cells that have reached the end of their life cycle, are the primary source of bilirubin production. The heme group within the globin chain of these red blood cells is responsible for the production of bilirubin. Unconjugated bilirubin is the form of bilirubin that is found in the bloodstream before it is conjugated with bile salts in the liver. In summary, bilirubin is produced by the breakdown of senescent erythrocytes in the liver, with the heme group within the globin chain being responsible for this process. Unconjugated bilirubin is the form of bilirubin that is found in the bloodstream before it is processed further in the liver.. 

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This Photo by Unknown Author is licensed under CC BY-SA

[Audio] We will be discussing the metabolism of bilirubin today. Bilirubin is a process that occurs in our bodies, where bilirubin is metabolized and eliminated. Bilirubin is produced when our red blood cells are destroyed, and the heme pigment is broken down into biliverdin, which is then converted into bilirubin. The unconjugated bilirubin is then bound to albumin and transported to the liver through the hepatic sinusoid. In the liver, bilirubin is conjugated with glucuronic acid and excreted into the bile, which is then secreted into the small intestine. The urobilinogen, which is produced during this process, is further metabolized into bilirubin in the kidneys. The bilinary system is responsible for the elimination of bilirubin from the body, which is excreted through the portal vein into the bile. It's important to note that high levels of bilirubin in the blood can be a sign of a liver or gallbladder problem, but it can also be caused by factors such as medication side effects or genetic disorders. We hope this information has been helpful. If you have any questions, please feel free to ask.. 

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[Audio] We address the responsibility of the spleen in removing foreign substances from the blood. As a highly vascular organ, the spleen plays a critical role in the body's defense against bacteria and viruses. The slow flow of blood in the spleen can lead to problems with filtration. The spleen is also a significant storage area for monocyte phagocyte cells in the red pulp, which play a vital role in the body's defense against foreign substances.. 

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SPLEEN – filtration of all foreighn material from blood
-Highly vascular organ ,Sluggish flow of blood
-Major repository for monocyte phagocyte cells in red pulp

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[Audio] We will now be discussing bilirubin metabolism. Bilirubin is a yellowish-brown pigment that is found in the blood and is produced by the breakdown of red blood cells. The spleen is a blood filter that plays a crucial role in the metabolism of bilirubin. When blood from the splenic artery enters the spleen, it is filtered through the hilum and then divided into smaller branches that enter the splenic parenchyma. As these branches gradually decrease in diameter, smaller arterioles leave the dense connective tissue of trabeculae entering the parenchyma, where they are surrounded by pals. The spleen is a fist-sized organ located in the left upper quadrant of the abdomen and is the largest lymphoid organ in the body. It has several important functions, including filtering blood, maintaining immune response balance, and recycling iron. It can also serve as a reservoir for additional blood in situations of acute or chronic blood loss, as well as an alternative site for hematopoiesis outside of bone marrow. However, it is not a vital organ, and people can live without it. Its unique functions can be replaced by other lymphoid organs. In conclusion, the spleen plays a crucial role in bilirubin metabolism.. 

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Since the spleen is a blood filter, one has to assume that it is a highly vascular organ. Blood from the splenic artery enters the spleen through the hilum. From there, the artery divides into smaller branches that enter the splenic parenchyma following the course of trabeculae. Together with the trabeculae, the arteries branch throughout the parenchyma and gradually decrease in diameter. Eventually, smaller arterioles leave the dense connective tissue of trabeculae entering the parenchyma, where they are surrounded by PALS.
 The spleen is a fist sized organ located in the left upper quadrant of the abdomen. It is the largest lymphoid organ and thus the largest filter of blood in the human body. The spleen  has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs.
 Special histological features define several important functions of the spleen, such as filtering blood, maintaining immune response balance and recycling iron. The spleen can also serve as a reservoir for additional blood in situations of acute or chronic blood loss (such as bleeding or anemia), as well as an alternative site for hematopoiesis (formation of blood cells and platelets) outside of bone marrow. Even though the spleen has a few unique functions that can't be replaced by other lymphoid organs, it is not a vital organ and people can live without it.

BLOOD Platelets RBC s, MONO MAC Lysozyme. SENESCENT RBC’S. 

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BLOOD
Platelets
RBC s,
MONO
MAC
Lysozyme

[Audio] Good morning, ladies and gentlemen. I am delighted to discuss Bilirubin metabolism and its importance in higher education. Bilirubin is a natural byproduct of the breakdown of red blood cells and is vital for human health. However, when it accumulates in the body, it can lead to jaundice, a yellowing of the skin and eyes. In higher education, understanding Bilirubin metabolism is critical for both students and faculty. It is essential for medical professionals to be aware of the signs and symptoms of jaundice, as well as the potential complications that can arise from it. Furthermore, comprehending Bilirubin metabolism can help students and faculty make informed decisions about their health and well-being. For instance, students should be aware of the potential risks associated with certain medications or supplements that can affect Bilirubin metabolism. Overall, Bilirubin metabolism is a complex and essential topic in higher education. By understanding it, we can enhance our overall health and well-being and make more informed decisions about our health and well-being.. 

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HELLO EVERYBODY
 HOW ARE YOU TODAY
 ITS TIME TO DO PARTY AND SAY HELLO

[Audio] We are pleased to welcome you to today's presentation on Bilirubin Metabolism. Blue is prominently featured in this slide as it has a significant role in the metabolism of bilirubin, a substance that is produced in the liver and plays a crucial role in the body's ability to detoxify harmful substances.. 

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HGSHCGHCASJCNB BSCHAHDCBAHSVCH VSGADFBXVSABVCB(2,3. 

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HGSHCGHCASJCNB BSCHAHDCBAHSVCH
 VSGADFBXVSABVCB(2,3

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BILIRUBIN METABOLISM

Bilirubin is a yellow pigment that is produced in the liver when red blood cells (erythrocytes) are broken down. Senescent erythrocytes, which are red blood cells that have reached the end of their life cycle, are the primary source of bilirubin production. The heme group within the globin chain of these red blood cells is responsible for the production of bilirubin. Unconjugated bilirubin is the form of bilirubin that is found in the bloodstream before it is conjugated with bile salts in the liver. In summary, bilirubin is produced by the breakdown of senescent erythrocytes in the liver, with the heme group within the globin chain being responsible for this process. Unconjugated bilirubin is the form of bilirubin that is found in the bloodstream before it is processed further in the liver.

avatar

 This Photo by Unknown Author is licensed under CC BY-SA

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We will be discussing the metabolism of bilirubin today. Bilirubin is a process that occurs in our bodies, where bilirubin is metabolized and eliminated. Bilirubin is produced when our red blood cells are destroyed, and the heme pigment is broken down into biliverdin, which is then converted into bilirubin. The unconjugated bilirubin is then bound to albumin and transported to the liver through the hepatic sinusoid. In the liver, bilirubin is conjugated with glucuronic acid and excreted into the bile, which is then secreted into the small intestine. The urobilinogen, which is produced during this process, is further metabolized into bilirubin in the kidneys. The bilinary system is responsible for the elimination of bilirubin from the body, which is excreted through the portal vein into the bile. It's important to note that high levels of bilirubin in the blood can be a sign of a liver or gallbladder problem, but it can also be caused by factors such as medication side effects or genetic disorders. We hope this information has been helpful. If you have any questions, please feel free to ask.

We address the responsibility of the spleen in removing foreign substances from the blood. As a highly vascular organ, the spleen plays a critical role in the body's defense against bacteria and viruses. The slow flow of blood in the spleen can lead to problems with filtration. The spleen is also a significant storage area for monocyte phagocyte cells in the red pulp, which play a vital role in the body's defense against foreign substances.

We will now be discussing bilirubin metabolism. Bilirubin is a yellowish-brown pigment that is found in the blood and is produced by the breakdown of red blood cells. The spleen is a blood filter that plays a crucial role in the metabolism of bilirubin. When blood from the splenic artery enters the spleen, it is filtered through the hilum and then divided into smaller branches that enter the splenic parenchyma. As these branches gradually decrease in diameter, smaller arterioles leave the dense connective tissue of trabeculae entering the parenchyma, where they are surrounded by pals. The spleen is a fist-sized organ located in the left upper quadrant of the abdomen and is the largest lymphoid organ in the body. It has several important functions, including filtering blood, maintaining immune response balance, and recycling iron. It can also serve as a reservoir for additional blood in situations of acute or chronic blood loss, as well as an alternative site for hematopoiesis outside of bone marrow. However, it is not a vital organ, and people can live without it. Its unique functions can be replaced by other lymphoid organs. In conclusion, the spleen plays a crucial role in bilirubin metabolism.

 Since the spleen is a blood filter, one has to assume that it is a highly vascular organ. Blood from the splenic artery enters the spleen through the hilum. From there, the artery divides into smaller branches that enter the splenic parenchyma following the course of trabeculae. Together with the trabeculae, the arteries branch throughout the parenchyma and gradually decrease in diameter. Eventually, smaller arterioles leave the dense connective tissue of trabeculae entering the parenchyma, where they are surrounded by PALS.
 The spleen is a fist sized organ located in the left upper quadrant of the abdomen. It is the largest lymphoid organ and thus the largest filter of blood in the human body. The spleen  has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs.
 Special histological features define several important functions of the spleen, such as filtering blood, maintaining immune response balance and recycling iron. The spleen can also serve as a reservoir for additional blood in situations of acute or chronic blood loss (such as bleeding or anemia), as well as an alternative site for hematopoiesis (formation of blood cells and platelets) outside of bone marrow. Even though the spleen has a few unique functions that can't be replaced by other lymphoid organs, it is not a vital organ and people can live without it.

slide11-hotlink3

Good morning, ladies and gentlemen. I am delighted to discuss Bilirubin metabolism and its importance in higher education. Bilirubin is a natural byproduct of the breakdown of red blood cells and is vital for human health. However, when it accumulates in the body, it can lead to jaundice, a yellowing of the skin and eyes. In higher education, understanding Bilirubin metabolism is critical for both students and faculty. It is essential for medical professionals to be aware of the signs and symptoms of jaundice, as well as the potential complications that can arise from it. Furthermore, comprehending Bilirubin metabolism can help students and faculty make informed decisions about their health and well-being. For instance, students should be aware of the potential risks associated with certain medications or supplements that can affect Bilirubin metabolism. Overall, Bilirubin metabolism is a complex and essential topic in higher education. By understanding it, we can enhance our overall health and well-being and make more informed decisions about our health and well-being.

We are pleased to welcome you to today's presentation on Bilirubin Metabolism. Blue is prominently featured in this slide as it has a significant role in the metabolism of bilirubin, a substance that is produced in the liver and plays a crucial role in the body's ability to detoxify harmful substances.