The Amyloid Hypothesis
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The Amyloid Hypothesis.
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Alois Alzheimer.
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Beta- amyloid. Alzheimer’s.
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Amyloid-beta Amyloid Precursor Proteins (APP). Cell membrane.
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Amyloid-beta. APP Gene PSEN1 Gene PSEN2 Gene. Mutations.
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Inflammation. Amyloid plaque. Cell death. Tau tangle formation.
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Inflammation Amyloid plaque Cell death Tau tangle formation Synapse dysfunction.