Thyroid Gland: Laboratory Analysis

Published on
Scene 1 (0s)

Thyroid Gland: Laboratory Analysis

Grezelou A. Amosin

Scene 2 (7s)

TSH Test Thyroid-Stimulating Hormone 3 Generations of assays: First Generation TSH - all the assays are capable of diagnosing primary hypothyroidism Second ( TSH Immunometric assays)- can effectively screen hyperthyroidism Third ( Chemiluminometric assays- less likely give false-negative results, but can accurately distinguish between euthyroidism and hyperthyroidism

Grezelou A. Amosin

Scene 3 (22s)

T4 Tests known as the thyroxine test A high level of T4 indicates an overactive thyroid (hyperthyroidism) Most of the T4 in your body is bound to protein. T3 Tests Checks for levels of the hormone triiodothyronine. Usually ordered if T4 tests and TSH tests suggest hyperthyroidism.

Grezelou A. Amosin

Scene 4 (38s)

Radioimmunoassay (RIA)/ Chemiluminometric assay/ Similar immunometric Technique Is used to measured the serum of T4 and T3 Double Antibody RIA/ Enzyme-linked immunoassay/ Immunoradiometric assay/ Immunochemiluminescent assay/ THYROGLOBULIN - is a protein synthesize and secreted exclussively by thyroid follicular cells Proof of the presence of thyroid tissue. an ideal tumor marker for thyroid cancer patients

Grezelou A. Amosin

Scene 5 (55s)

Thyroid-Stimulating Antibodies (TRAb)/ Thyroid-Stimulating Immunoglobulin (TSI) The most common cause of Hyperthyroidism is an autoimmune disorder called Grave’s disease.

Scene 6 (1m 5s)

OTHER TOOLS FOR THYROID EVALUATION Nuclear Medicine Evaluation Radioactive iodine - assessing the metabolic activity of thyroid tissue and assisting in the evaluation and treatment of thyroid cancer. Radioactive Iodine Uptake (RAIU) - measure how much tracer the thyroid gland absorbs from the blood. Thyroid Ultrasound - capable of detecting even thyroid nodules. Fine-Needle Aspiration Biopsy - is often the first step and the most acucrate tool in the evaluation of thyroid nodules.

Grezelou A. Amosin