PowerPoint Presentation

[Virtual Presenter] Professor Dr. S. Papageorgiou, a renowned expert in the field of diabetic foot ulcer treatment, spearheads this groundbreaking study, bringing unparalleled expertise and innovation to the treatment of diabetic foot ulcers. The condition, which affects millions of people worldwide, causes significant discomfort, disability, and even loss of limbs. Our objective is to provide a comprehensive overview of this complex issue and present a cutting-edge solution that combines systemic and topical treatments..

[Audio] The diabetic foot condition progresses through several stages, each characterized by distinct symptoms and medical descriptions. These stages range from initial, where minor skin lesions appear, accompanied by mild discomfort, to severe, where the skin breaks down, and the risk of infection and amputation becomes significant. As the condition advances, the skin lesions deepen, and the individual may experience increasing pain and tenderness. Understanding the progression of the diabetic foot condition is crucial, as it informs the development of effective treatment strategies and the need for early intervention..

[Audio] Diabetic foot ulcers are a significant complication of diabetes, often leading to severe outcomes if not properly managed. Understanding the progression from initial to severe stages is crucial for effective treatment and prevention..

[Audio] A superficial ulcer, also known as a grade one ulcer, is characterized by its initial condition, which confines it to the epidermis and dermis without penetrating deeper layers. This results in limited tissue damage to the skin's surface, appearing as an open sore or wound. The ulcer typically displays a red and inflamed appearance, accompanied by possible surrounding callus formation..

[Audio] Diabetic Foot Ulcer complications can lead to severe consequences, including deep ulcers that extend into the subcutaneous tissue. Moderate condition ulcers, classified as Grade 2, pose a significant risk of infection due to the exposure of tendons, ligaments, or joints. The appearance of these ulcers may indicate the presence of infection, with signs such as drainage, swelling, and a foul odor..

[Audio] The description of Grade 3 is a deep ulcer accompanied by abscess formation or infection of the bone, osteomyelitis. This stage shows significant destruction of soft tissue and bone, often leading to systemic infection. The appearance of the foot may display severe infection symptoms, including increased redness, warmth, swelling, and purulent discharge..

[Audio] In this critical condition, localized gangrene affects part of the forefoot, causing necrosis of tissues due to inadequate blood supply. This leads to tissue death, resulting in the appearance of a blackened, dry, and shriveled area, indicating dead tissue..

[Audio] Severe cases of diabetic foot ulcers can result in widespread tissue death, causing extensive gangrene. This condition poses an immediate threat to the entire limb, necessitating urgent attention to prevent life-threatening complications. The affected foot typically exhibits large blackened areas, accompanied by a foul odor and clear signs of severe infection. If left untreated, this condition can ultimately lead to amputation, significantly diminishing a patient's quality of life..

[Audio] We have developed an advanced Diabetic Foot Ulcer treatment product designed to promote healing and prevent complications..

[Audio] Diabetes is a group of metabolic diseases characterized by high blood sugar resulting from a defect in insulin secretion, insulin action, or both. Diabetic Foot Ulcer is one of the major complications of the disease Diabetes, and it has a significant impact on the health status of affected patients. Diabetic Foot Ulcer complications can lead to various negative outcomes if not properly managed. These complications include ulcers and wounds, infection, and gangrene. Untreated wounds can become infected, leading to ulcers and potential amputation. Diabetic Foot Ulcers are prone to infection due to compromised immune function and poor circulation. If left untreated, infections can spread to the bone or bloodstream, leading to serious complications. Gangrene is the death of body tissue due to a lack of blood flow or a bacterial infection. Diabetic Foot Ulcer that becomes infected or does not heal can lead to gangrene, which may necessitate amputation of the affected area..

[Audio] Severe cases of Diabetic Foot Ulcer complications may require partial or complete amputation of the affected limb to prevent the spread of infection and save the patient's life. Chronic foot pain, difficulty walking, and frequent medical treatments can significantly impact a person's quality of life, affecting their ability to perform daily activities and lead an active lifestyle. Serious Diabetic Foot Ulcer complications often require hospitalization for wound care, infection management, or surgical intervention, leading to increased healthcare costs and potential complications. Severe Diabetic Foot Ulcer complications can result in permanent disability, affecting a person's mobility and independence. Individuals with diabetes who develop foot complications, such as ulcers or infections, are at a higher risk of premature death due to associated cardiovascular complications or systemic infections. Preventing and managing Diabetic Foot Ulcer complications through proper foot care, regular monitoring, and early intervention is crucial to avoid these negative outcomes and maintain overall health and well-being..

[Audio] The advanced Diabetic Foot Ulcer treatment product was developed to promote healing and prevent complications. The product works both topically and systemically, enabling it to address the root causes of the problem rather than just treating the symptoms. It provides effective relief from chronic foot pain, improves mobility, and reduces the risk of amputations and other complications. The treatment promotes healthy tissue growth and prevents further damage, allowing patients to regain control over their lives and live independently..

[Audio] The research results demonstrate that LYTONIC ™ is the most effective treatment for diabetic foot ulcers. By enhancing blood circulation in the affected area, it speeds up the healing process. Furthermore, it has no reported adverse reactions. LYTONIC ™ is available in two forms: gel and capsules. The gel functions topically, whereas the capsules offer systemic therapy. With its pioneering approach, LYTONIC ™ sets a new benchmark in diabetic foot ulcer care..

[Audio] Our revolutionary capsules, LYTONIC Plus, offer an effective solution for Diabetic Foot Ulcer, promoting healing and preventing complications. The capsules contain four active ingredients, including Melilotus Officinalis Dried Extract, alpha-Lipoic Acid, Coenzyme Q10, and Vitamin E. Each ingredient plays a crucial role in enhancing the body's natural healing processes, reducing inflammation and swelling, regenerating nerves, and protecting cells from damage. With its systemic and topical benefits, LYTONIC Plus provides a comprehensive approach to treating Diabetic Foot Ulcer, supporting the body's ability to heal and recover..

[Audio] The LYTONIC Plus capsules are a powerful oral supplement designed to support blood circulation, promote antioxidant action, and enhance the body's natural healing processes. These benefits are vital for diabetic foot ulcer treatment and overall skin repair..

[Audio] LYTONIC Plus™ improves blood circulation to the affected area, enhances tissue regeneration and cellular repair. Additionally, it reduces oxidative stress and inflammation, accelerating healing. Moreover, it promotes overall systemic health to support diabetic foot ulcer treatment. To achieve optimal results, take one to two capsules daily with water, as advised by healthcare professionals..

[Audio] The ingredients used in LYTONIC Gel ™ are Aqua, Glycerin, Carbomer, Melilotus Officinalis Extract, Disodium Acetyl Glucosamine Phosphate, Carboxypolymethylene, Caffeyl Glucoside, Sodium Hyaluronate, Copper Tripeptide-1, Sodium Hydroxide, Methylpropanediol, Caprylyl Glycol, and Phenylpropanol. This advanced gel utilizes nano technology to promote enhanced healing and prevent complications related to Diabetic Foot Ulcers. Designed for external use only, the gel comes in a tube of 40ml. Its active ingredients collaborate to provide hydration, antimicrobial protection, and accelerated tissue regeneration, thereby reducing the risk of further complications..

[Audio] LYTONIC Gel's mode of action involves its antioxidant properties, which improve blood circulation and strengthen the lymphatic system, leading to the removal of dead tissue in the affected area. Furthermore, it hydrates and revitalizes damaged skin cells, reduces inflammation, promotes tissue repair, enhances blood flow and oxygenation of tissues, and provides a soothing effect and anti-inflammatory action..

[Audio] Our revolutionary gel offers an effective solution for Diabetic Foot Ulcer, promoting healing and preventing complications. The innovative revitalizing nano complex works by revitalize, repairing, deep hydrating of skin, cells oxygenating, antioxidant, and skin detoxifying. This complex includes melilotus officinalis dried extract, copper tripeptide, phosphorylated amino-sugar, glycosylated polyphenols, and hyaluronic acid. These ingredients work together to accelerate healing, provide pain relief, prevent infection, and offer easy application..

[Audio] The LYTONIC Gel has numerous benefits, including topical healing and moisturizing, antimicrobial protection, enhanced tissue regeneration, accelerated healing, pain relief, preventing infection, and ease of application. Its formula speeds up the healing process of diabetic foot ulcers, offering soothing relief from pain and discomfort. Additionally, it safeguards against infection, thereby minimizing the risk of further complications. To utilize the LYTONIC Gel, one should first cleanse the affected area with mild soap and water, then apply a thin layer twice daily directly to the ulcer and surrounding skin. If necessary, cover the area with a sterile bandage, and repeat the application 2-3 times daily as instructed by healthcare professionals..

[Audio] Our treatment offers comprehensive care through both internal and external applications, addressing systemic and localized factors of Diabetic Foot Ulcer. The capsules enhance blood circulation and reduce internal inflammation, whereas the gel moisturizes, protects, and soothes the skin. By combining these two components, we expedite healing, minimize the likelihood of infection, and foster overall foot well-being..

[Audio] When LYTONIC Plus™ capsules and LYTONIC Gel ™ are used together, they provide a comprehensive approach to healing. The systemic support offered by LYTONIC Plus™ promotes blood circulation, reduces oxidative stress, and enhances cellular repair. Meanwhile, LYTONIC Gel ™ provides topical healing, directly hydrating and soothing the affected skin, enhancing local circulation, and accelerating tissue repair. This synergy enables both internal and external healing, resulting in faster recovery from diabetic foot ulcers..

[Audio] The synergistic effects of LYTONIC capsules and a gel have been studied through a randomized clinical trial on diabetic foot ulcers conducted by Professor Dr. S. Papageorgiou, our Research and Development Director, who led the project with his team. The results were published in December 2022..

[Audio] Professor Dr. S. Papageorgiou, a distinguished Research and Development Director, spearheaded this groundbreaking study, bringing unparalleled expertise and innovation to the field of diabetic foot ulcer treatment. With an illustrious career rooted in advanced medical research and clinical application, he is known for his commitment to developing transformative therapeutic solutions. Operating from the esteemed Attikon General University Hospital of Athens, an internationally recognized center for research and healthcare excellence, he has consistently pushed the boundaries of scientific inquiry. His leadership in combining systemic and topical approaches, as demonstrated in this study, underscores his dedication to enhancing patient outcomes and addressing critical healthcare challenges..

[Audio] The Attikon General University Hospital of Athens is a beacon of healthcare innovation and academic excellence in Greece. Equipped with state-of-the-art facilities, it plays a dual role as a leading clinical center and a pioneering research institution. Its strategic focus encompasses cutting-edge medical treatments, patient-centered care, and groundbreaking clinical trials that contribute to global advancements in healthcare. The hospital is renowned for its collaboration with esteemed researchers and professionals, fostering an environment that bridges science and practice. This institution has become a preferred site for high-impact studies, particularly in areas such as diabetic care, wound healing, and chronic disease management..

[Audio] The patient demographics and target ulcer characteristics reveal that there are a total of 24 patients, comprising four distinct groups. The control group consists of six patients, including four males and two females, with an average ulcer area of 12.5 square centimeters. Similarly, the capsules-only group comprises six patients, consisting of four males and two females, with an average ulcer area of 12.3 square centimeters. The gel-only group has six patients, including four males and two females, with an average ulcer area of 12.4 square centimeters. The capsules-plus-gel group also consists of six patients, comprising four males and two females, with an average ulcer area of 12.2 square centimeters. In summary, the study involves 16 male patients and eight female patients..

[Audio] The results demonstrate that the mean ulcer surface area changed significantly within the 6-8 week period. The control group initially presented with a mean ulcer area of 12.5 cm², which decreased by 3.5 cm² to 12.0 cm² after treatment. In contrast, the capsules-only group started with a mean ulcer area of 12.3 cm², which reduced by 3.8 cm² to 8.5 cm² after treatment. Similarly, the gel-only group began with a mean ulcer area of 12.4 cm², which decreased by 3.4 cm² to 9.0 cm² after treatment. Notably, the combination therapy group, utilizing both capsules and gel, exhibited the most substantial reduction in mean ulcer area, decreasing from 12.2 cm² to 5.0 cm², a change of 7.2 cm²..

[Audio] The LYTONIC Capsules alone achieved a 30.9% reduction in wound size, whereas the LYTONIC Gel alone resulted in a 27.4% reduction. However, when both products were used together, the percentage of wound reduction increased significantly to 59.0%. In comparison, the control group, which received no treatment, showed a mere 4.0% reduction in wound size. These findings illustrate the efficacy of LYTONIC's combination therapy in promoting substantial advancements in wound healing..

[Audio] The results demonstrate that all groups experienced significant decreases in inflammatory markers, with the most pronounced reduction occurring in the capsules plus gel group. Similarly, the oxidative stress markers decreased significantly in all groups, with the greatest decline observed in the capsules plus gel group. These findings imply that the combination of systemic and topical treatments may exhibit a synergistic effect in reducing inflammation and oxidative stress in patients with diabetic foot ulcers..

[Audio] The LYTONIC Gel has a mechanism of action that includes hydrating the skin, accelerating tissue repair, protecting against infections, encouraging skin regeneration, speeding up the healing process, providing pain relief, preventing infection, and being easy to apply. The gel contains ingredients such as aqua, glycerin, sodium hyaluronate, caffeyl glucoside, caprylyl glycol, copper tripeptide-1, and sodium hyaluronate. The LYTONIC Gel is used to treat diabetic foot ulcers, and its benefits include accelerated healing, pain relief, prevention of infection, and ease of application. The dosage is simple, requiring only one step: cleaning the affected area and applying the gel..

[Audio] The results show a significant reduction in inflammatory markers both before and after treatment. This indicates that our unique medicine is effective in reducing inflammation, which is a crucial factor in the healing process of diabetic foot ulcers. The data suggests that our treatment approach not only improves wound closure but also addresses the underlying causes of chronic wounds..

[Audio] The data shows that oxidative stress markers decreased significantly after treatment across all groups. This indicates that the treatment was effective in reducing oxidative stress, which is a key factor in the development and progression of diabetic foot ulcers. The reduction in oxidative stress markers suggests that the treatment may have helped to promote wound healing and reduce the risk of further complications..

[Audio] The results of this study demonstrate that combining LYTONIC 500mg Capsules and LYTONIC Gel leads to significant synergistic effects in treating diabetic foot ulcers. Compared to other treatments, this combined therapy achieves the highest rate of wound reduction, indicating faster healing. Additionally, it shows substantial improvements in inflammatory markers and oxidative stress markers, highlighting its anti-inflammatory and antioxidant properties. Furthermore, the combined treatment accelerates and effectively reduces ulcer surface area, showcasing the benefits of both systemic and topical therapies. This innovative approach has the potential to significantly improve patient outcomes and enhance overall quality of life by reducing the burden of complications..

[Audio] The revolutionary nano complex from Bochéry LAB ESTHÉTIQUE advances the recovery of diabetic foot ulcers with innovation and efficacy..

[Audio] The revolutionary nano complex has been designed to advance the recovery of diabetic foot ulcers with innovation and efficacy. We have successfully achieved this goal through our unique approach to treating these ulcers both systematically and topically. Our team at Bochéry LAB ESTHÉTIQUE has worked tirelessly to develop this groundbreaking technology..